The learning process nowadays is often experience disturbance and problem such as excessive number of students so that its development is difficult to monitor and lack of concentration from students in understanding the courses material as well as still using textbooks provided by school. The research objective was to implement ASSURE model in application development of natural science learning in order to support the learning process. Method used in this study was research and development for learning application that can be used in learning process of natural science subject. This research had produced the learning application for natural science subject. Software used in development and producing of learning application was Netbeans IDE 7.4, JDK 7 as Java interpreter and AppServ Version 2.5.9 as database. ASSURE model was used to develop learning application by using black box test method. It can be concluded that learning application for natural science subject had fulfill the stated criteria in term of display, operation and interaction aspects, respectively.
Keywords: ASSURE, Black Box Test, Software